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            Bioprocess Applications | Corning Bioprocessing Applications | Corning

            Bridge the Gap Between R&D and Production

            Bridge the Gap Between R&D and Production

            From research and development to manufacturing, Corning is proud to offer the latest innovative technology to support your advanced therapy applications. From vaccine production to advanced therapy applications, Corning can supply the tools to get you there.

            Our cell expansion platforms, from the new Ascent? Fixed Bed Reactor (FBR) System to the trusted HYPERStack?, HYPERFlask?, and CellSTACK? technologies, are proven to increase efficiency in scale-up, while continuing to deliver reliability and reproducibility, resulting in increased cell viability and yield. ?Several of our platforms feature closed systems or automation—thereby reducing risk of contamination, variability, and human error.

            Working with these tools supports efficient, successful scale-up, while reducing cost and speeding up time to market, providing a path for your research to translate from the lab to life changing treatments and therapies. Look to Corning’s years of experience in cell culture innovation and our team of field service experts to guide you along your journey to discovery.

            From Bench to Billions: Facilitating Scale-Up of Adherent Cultures for Cell and Gene Therapies

            Applications

            Learn More About Our Bioprocess Applications

            Vaccine Manufacturing

            Vaccine Manufacturing

            Vaccine Manufacturing

            From HYPERStack and CellSTACK culture chambers to microcarriers and the new Ascent FBR System, Corning provides the full range of tools you'll need to successfully perform and improve adherent-based cultures for vaccine scale-up and production.

            From HYPERStack and CellSTACK culture chambers to microcarriers and the new Ascent FBR System, Corning provides the full range of tools you'll need to successfully perform and improve adherent-based cultures for vaccine scale-up and production.

            Learn More
            Immune Cell Therapy

            Immune Cell Therapy

            Immune Cell Therapy

            Look to Corning for clinical cell expansion platforms that can help you scale from research to commercial production. Corning understands your need for clinical cell expansion platforms that scale from research to commercial production to assist in your immune cell therapy research.

            Look to Corning for clinical cell expansion platforms that can help you scale from research to commercial production. Corning understands your need for clinical cell expansion platforms that scale from research to commercial production to assist in your immune cell therapy research.

            Learn More
            Gene Therapy

            Gene Therapy

            Gene Therapy

            Corning is working to address the recent surge of interest in gene therapy and the increase in the use of modular manufacturing set-ups for viral vector production, allowing researchers to respond to ever-evolving production needs and enabling a smooth transition from process development to manufacturing.

            Corning is working to address the recent surge of interest in gene therapy and the increase in the use of modular manufacturing set-ups for viral vector production, allowing researchers to respond to ever-evolving production needs and enabling a smooth transition from process development to manufacturing.

            Learn More
            Stem Cell Therapy

            Stem Cell Therapy

            Stem Cell Therapy

            Corning offers a wide range of platforms and surface technologies to help drive your stem cell therapy research forward.

            Corning offers a wide range of platforms and surface technologies to help drive your stem cell therapy research forward.

            Learn More
            Extracellular Vesicles

            Extracellular Vesicles

            Extracellular Vesicles

            Corning offers a line of products designed for large-scale of stem cell-derived extracellular vesicles (EVs) to impact regenerative medicine and the treatment of inflammatory conditions.

            Corning offers a line of products designed for large-scale of stem cell-derived extracellular vesicles (EVs) to impact regenerative medicine and the treatment of inflammatory conditions.

            Learn More
            Cell Production

            Cell Production

            Cell Production

            Corning’s cell culture solutions support your cell production goals, orchestrate discoveries in your lab and scale-up cell expansion to mass production.

            Corning’s cell culture solutions support your cell production goals, orchestrate discoveries in your lab and scale-up cell expansion to mass production.

            Learn More
            Seed Train

            Seed Train

            Seed Train

            Whether utilizing suspension or adherent cell culture, an optimized seed train strategy is critical to a successful scale-up.

            Whether utilizing suspension or adherent cell culture, an optimized seed train strategy is critical to a successful scale-up.

            Learn More
            Expansion and Processing

            Expansion and Processing

            Expansion and Processing

            Choosing the right cell culture platform is key to meeting production goals.

            Choosing the right cell culture platform is key to meeting production goals.

            Learn More
            Harvest and Cryopreservation

            Harvest and Cryopreservation

            Harvest and Cryopreservation

            Closed system solutions can help reduce contamination risk and keep cells viable.

            Closed system solutions can help reduce contamination risk and keep cells viable.

            Learn More

            Products

            End-to-End Bioprocess Solutions for Scaling-up

            Blog Series

            Best Practices for Vaccine Production

            Best Practices for Vaccine Production

            Best Practices for Vaccine Production

            Discover four best practices for scaling up vaccine production process development from an expert in the field.

            Discover four best practices for scaling up vaccine production process development from an expert in the field.

            Learn More
            Automated Manipulator

            Optimize Your Viral Vector Workflow

            Optimize Your Viral Vector Workflow

            Learn about the latest trends in viral vector production to help enhance vaccine research development.

            Learn about the latest trends in viral vector production to help enhance vaccine research development.

            Learn More
            Chris Suarez, Ph.D.

            Vaccine Production: Which Platform Is Best?

            Vaccine Production: Which Platform Is Best?

            Making the right choice requires scientists to consider a range of factors, from surface area to scale.

            Making the right choice requires scientists to consider a range of factors, from surface area to scale.

            Learn More
            Dyno Therapeutics Scaling Up AAV Production using Ascent Fixed Bed Bioreactor System

            Dyno Therapeutics Scaling Up AAV Production using Ascent Fixed Bed Bioreactor System

            Dyno Therapeutics Scaling Up AAV Production using Ascent Fixed Bed Bioreactor System

            Learn how Corning scale-up solutions are assisting our customers with their gene therapy development.

            Learn how Corning scale-up solutions are assisting our customers with their gene therapy development.

            Learn More
            X-LAB

            How Can You Help Reduce Contamination Risk?

            How Can You Help Reduce Contamination Risk?

            Safeguarding against contamination risk is critical in immunotherapy applications. Discover how.

            Safeguarding against contamination risk is critical in immunotherapy applications. Discover how.

            Learn More
            Adeno-Associated Virus and Lentiviral Vectors

            Adeno-Associated Virus and Lentiviral Vectors

            Adeno-Associated Virus and Lentiviral Vectors

            AAV and LV vectors can be appealing alternatives to adenoviruses for researchers engaged in viral vector work. Let’s compare the two.

            AAV and LV vectors can be appealing alternatives to adenoviruses for researchers engaged in viral vector work. Let’s compare the two.

            Learn More
            Comparing Suspension and Adherent Cell Culture

            Comparing Suspension and Adherent Cell Culture

            Comparing Suspension and Adherent Cell Culture

            Vessel choice is influenced by a myriad of operational and biological factors, such as scale, resources, timing, cell type, and how much — or how little — culture inspection and parameter control is required.

            Vessel choice is influenced by a myriad of operational and biological factors, such as scale, resources, timing, cell type, and how much — or how little — culture inspection and parameter control is required.

            Learn More
            Customizing Cell Culture Media

            Customizing Cell Culture Media

            Customizing Cell Culture Media

            There are five important things to consider when determining how to customize your cell culture media or reagent.

            There are five important things to consider when determining how to customize your cell culture media or reagent.

            Learn More

            Featured Resources

            Guide to Extracellular Vesicles

            Guide to Extracellular Vesicles

            With more efficient and consistent production methods, researchers will be able to harness the enormous potential of EVs for clinical diagnostics, prognostics, and therapeutics.

            Download

            Cell Therapy Ebook

            Cell Therapy Ebook: A Comprehensive Look at Key Elements of Cell Production Success

            From research scale to clinical and commercial manufacturing, this free downloadable resource offers key considerations and technological expertise for cell therapy production and therapeutic candidate development.

            Download

            Achieving High Yield, Versatility, and Scalability for Adherent Cell Culture with Circulation/Perfusion Systems

            Achieving High Yield, Versatility, and Scalability for Adherent Cell Culture with Circulation/Perfusion Systems

            Learn about circulation/perfusion adherent cell culture platforms and how Corning CellCube offers cost-effective, high-yield cell production.

            Learn More

            Tales, Tips & Teachable Moments from Applications Support Veterans

            Tales, Tips & Teachable Moments from Applications Support Veterans

            Field application scientists share their experience and expertise from decades of supporting cell culture scientists in academic, biotech and pharma settings

            Learn More

            Viral Vector Manufacturing and Cell Harvesting from a Single Bioreactor?

            Viral Vector Manufacturing and Cell Harvesting from a Single Bioreactor?

            Corning experts recommend the Ascent Fixed Bed Bioreactor as a solution for adherent cell harvesting and cell product capture.

            Learn More

            HYPERStack Vessels

            Increase the Yield of Bone Marrow-derived hMSCs using HYPERStack

            See how researchers were able to successfully yield over 870 million human bone marrow-derived MSCs can be obtained from a single HYPERStack 36-layer cell culture vessel.

            Learn More

            Scaling up with HYPER Technology eBook

            Ebook: Scaling up with HYPER Technology

            Download this guide to improving your scale-up efficiency with HYPER technology from Corning.

            Download

            Adherent vs. Suspension

            Adherent vs. Suspension Advantages & Disadvantages

            Use this infographic to explore which cell culture platform is right for your lab.

            Learn More

            Stack Facts

            STACK FACTS: Scaling Up from Research to Clinical Applications

            Use this guide to help you choose your ideal Corning vessel for scaling up. Whatever your work requires, Corning’s got you covered.

            Learn More

            Related Applications

            Cell Production

            Cell Production Cell Production

            Whether you're expanding suspension or adherent cell lines, we offer a full range of cell culture vessels, from a selection of single-use flasks to HYPER technology platforms and now the new Ascent FBR System.

            Whether you're expanding suspension or adherent cell lines, we offer a full range of cell culture vessels, from a selection of single-use flasks to HYPER technology platforms and now the new Ascent FBR System.

            Learn More
            Advanced Therapies

            Advanced Therapies Advanced Therapies

            From gene therapy to vaccine development, there is much promise in advanced therapy research and the potential life changing treatments they could deliver. Let Corning be your guide with technologies like Ascent FBR system, HYPER technologies, and more.

            From gene therapy to vaccine development, there is much promise in advanced therapy research and the potential life changing treatments they could deliver. Let Corning be your guide with technologies like Ascent FBR system, HYPER technologies, and more.

            Learn More

            Webinars

            Support

            Field Applications Support

            Build a Scale-up Strategy
            Field Applications Support: We’re with You Every Step of the Way

            We’re With You Every Step of the Way

            We’re With You Every Step of the Way

            Contact Us
            In the complex world of cell and gene therapy, having a seasoned partner to guide you through uncharted production territory is critical to success.
            ?
            Corning’s Field Applications?Scientists have a deep understanding of how the cell culture environment can impact overall cell health, expansion and activity, and how to tailor a culture to suit specific needs. We work with scientists like you to overcome complex manufacturing challenges and streamline the path to production.
            In the complex world of cell and gene therapy, having a seasoned partner to guide you through uncharted production territory is critical to success.
            ?
            Corning’s Field Applications Scientists have a deep understanding of how the cell culture environment can impact overall cell health, expansion and activity, and how to tailor a culture to suit specific needs. We work with scientists like you to overcome complex manufacturing challenges and streamline the path to production.
            Contact Us
            Quality
            Quality that Supports the Path from Research to Production

            Quality that Supports the Path from Research to Production

            Quality that Supports the Path from Research to Production

            With more than 100 years of experience in life sciences, Corning deeply understands the importance of quality. We offer:

            • A proven quality management system
            • Certificates and regulatory?documentation
            • BSE/TSE and Sterility

            ?

            Our tried and true manufacturing processes and practices are designed to ensure that every product delivers consistent, reliable results.

            With more than 100 years of experience in life sciences, Corning deeply understands the importance of quality. We offer:

            • A proven quality management system
            • Certificates and regulatory documentation
            • BSE/TSE and Sterility

            ?

            Our tried and true manufacturing processes and practices are designed to ensure that every product delivers consistent, reliable results.

            Connect with Corning

            Connect with Corning

            Contact Us
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